Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964976 | 0.76 | BCHE (0.63) | MAPTDYRK1ACLK4DYRK1BALDH1A1 | |
| SCHEMBL2450795 | 0.76 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL6749573 | 0.75 | PTGDR2 (0.65) | PTGDR2 | |
| SCHEMBL2444500 | 0.71 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL10055018 | 0.70 | NOS1 (0.63) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL2446963 | 0.70 | PTGDR2 (0.60) | PTGDR2KDM1A | |
| SCHEMBL2305041 | 0.70 | MAPT (0.83) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6751910 | 0.69 | PTGDR2 (0.57) | PTGDR2ALDH1A1LMNASMN1; SMN2KDM1A | |
| SCHEMBL2449413 | 0.68 | PTGDR2 (0.57) | PTGDR2ALDH1A1 | |
| SCHEMBL3132340 | 0.68 | MAPT (0.87) | MAPTALDH1A1LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058265-A1 | COMPOUND LIBRARIES OF 2,3-SUBSTITUTED PYRAZINE DERIVATIVES CAPABLE OF BINDING TO G-PROTEIN COUPLED RECEPTORS | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |