Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 3/20 | 0.87 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.87 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.87 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.87 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.87 |
| ▸ | DPP4 | P27487 | 1/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.87 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.87 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.87 |
| ▸ | GAPDH | P04406 | 1/20 | 0.87 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.87 |
| ▸ | STAT6 | P42226 | 1/20 | 0.87 |
| ▸ | PI4KA | P42356 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.87 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.87 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.87 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.87 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL4396199 | 1.00 | ADORA3 (0.87) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL4401875 | 1.00 | ADORA3 (0.87) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL4138547 | 0.97 | ADORA3 (0.89) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL10579680 | 0.96 | ADORA3 (0.87) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL9426528 | 0.94 | ADORA3 (0.89) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL5034955 | 0.94 | ADORA3 (0.77) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL5034951 | 0.94 | ADORA3 (0.77) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL28588050 | 0.94 | ADORA3 (0.80) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL27849525 | 0.93 | ADORA3 (0.91) | ADORA3DOT1LDPP4MEN1SLC28A1 | |
| Adenosine SCHEMBL27541540 | 0.93 | ADORA3 (0.95) | ADORA3DOT1LDPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117361680-A | Preparation method and application method of organic matter extractant in wastewater | 中钢集团鞍山热能研究院有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20040038373-A1 | Apoptotic EBV-transformed lymphocytes, a therapeutic agent for post-transplant lymphoproliferative disorder | PLATZ MATTHEW S (US) | 2004-02-26 | — | — | US | disclosed |
| WO-2003054150-A2 | APOPTOTIC EBV-TRANSFORMED LYMPHOCYTES, A THERAPEUTIC AGENT FOR POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-07-03 | — | — | WO | disclosed |