Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752283 | 0.94 | F10 (0.52) | F10F2PRSS1KCNH2 | |
| SCHEMBL6747940 | 0.91 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6859538 | 0.88 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6749865 | 0.85 | F10 (0.51) | F10F2PRSS1KCNH2 | |
| SCHEMBL7099152 | 0.85 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6750749 | 0.85 | F10 (0.59) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6749876 | 0.84 | F10 (0.50) | F10F2PRSS1KCNH2 | |
| SCHEMBL6564612 | 0.83 | F10 (0.55) | F10F2PRSS1KCNH2 | |
| SCHEMBL6746084 | 0.83 | NAMPT (0.42) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6749873 | 0.82 | F10 (0.54) | F10F2PRSS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | MERCK PATENT GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | F11, F2, F12 | F10 6/4885F2 2/4885PRSS1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.