Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748713 | 0.87 | MEN1 (0.47) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL6739597 | 0.78 | POLB (0.49) | MAPTHTTCYP2C9MEN1KMT2A | |
| SCHEMBL6732799 | 0.72 | MAPT (0.44) | MAPTHTTMEN1KMT2APTGS2 | |
| SCHEMBL418889 | 0.72 | MAPT (0.47) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL6733203 | 0.72 | MEN1 (0.45) | MAPTCYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL6735096 | 0.70 | MEN1 (0.46) | MAPTHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL6727745 | 0.69 | ALDH1A1 (0.60) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL50462 | 0.68 | SRD5A2 (0.74) | MAPTMEN1KMT2AL3MBTL1NR4A1 | |
| SCHEMBL9442387 | 0.68 | SRD5A2 (0.74) | MAPTMEN1KMT2AL3MBTL1NR4A1 | |
| Hydrochloric Acid SCHEMBL4594202 | 0.66 | SRD5A2 (0.71) | MAPTMEN1KMT2AL3MBTL1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713503-B1 | 1-(2,4-DIMETHYL-PHENYL)-2,4-DIHYDROXY-3-(4-METHYL-BENZOYL)-5-OXO-2,5 -DIHYDRO-1H-PYRROLE-2-CARBOXYLIC ACID METHYL ESTER | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-30 | — | — | US | disclosed |
| US-6703426-B1 | 4-(4-CHLORO-PHENYL)-2,4-DIOXO-3- (PHENYL-HYDRAZONO)-BUTYRIC ACID ETHYL ESTER IS ADMINISTERED | UNIVERSITY OF CENTRAL FLORIDA | 2004-03-09 | — | — | US | disclosed |
| US-6638975-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-10-28 | — | — | US | disclosed |
| US-6602907-B1 | Treatment of breast cancer | UNIVERSITY OF CENTRAL FLORIDA | 2003-08-05 | — | — | US | disclosed |