Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NCF1 | P14598 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498821 | 0.81 | NCF1 (0.50) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL1131286 | 0.81 | NCF1 (0.50) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| Phosphine SCHEMBL23753735 | 0.79 | MAPT (0.49) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL6026855 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL7942319 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL17440166 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL5593982 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL4458474 | 0.77 | MAPT (0.47) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL9826905 | 0.77 | NCF1 (0.52) | MAPTMEN1KMT2ANCF1CYP1A2 | |
| SCHEMBL29392943 | 0.77 | KDM4E (0.53) | MAPTMEN1KMT2ANCF1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040115173-A1 | Method of treating inflammation, particularly diabetes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-06-17 | — | — | US | disclosed |
| WO-2002066619-A1 | METHODS OF TREATING INFLAMMATION, PARTICULARLY DIABETES | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2002-08-29 | — | — | WO | disclosed |
| EP-1221974-A2 | MAGNETIC TARGETED CARRIER | Ferx Incorporated (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001028587-A2 | MAGNETIC TARGETED CARRIER | FERX INCORPORATED (US) | 2001-04-26 | — | — | WO | disclosed |