Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752759 | 0.98 | MAPT (0.46) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL7823783 | 0.92 | MAPT (0.53) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL7809242 | 0.90 | MAPT (0.51) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL15923031 | 0.90 | MAPT (0.51) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL9689470 | 0.90 | MAPT (0.51) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL2381711 | 0.90 | MAPT (0.51) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL4218226 | 0.86 | DRD2 (0.52) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL7230240 | 0.82 | TDP1 (0.53) | MAPTL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8434882 | 0.82 | CA12 (0.61) | MAPTL3MBTL1TDP1HPGDATM | |
| SCHEMBL11615899 | 0.82 | KCNA3 (0.55) | L3MBTL1DRD3KCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706739-B2 | TREATING ENTEROVIRUS INFECTION | NATIONAL HEALTH RESEARCH INSTITUTE (TW) | 2004-03-16 | — | — | US | disclosed |
| US-20030087936-A1 | Imidazolidinone compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2003-05-08 | — | — | US | disclosed |
| US-4937268-A | TREATMENT OF ASTHMA, CHRONIC BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0286242-A2 | Ethanolamine derivates, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087936-A1 | Imidazolidinone compounds | EIF2AK2, ZC3HAV1, EMG1 | MAPT 3873/4885L3MBTL1 252/4885TDP1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.