⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721829 | 0.65 | — | — | |
| SCHEMBL15561929 | 0.65 | — | — | |
| SCHEMBL1040932 | 0.60 | — | — | |
| SCHEMBL1528079 | 0.60 | — | — | |
| SCHEMBL5685900 | 0.58 | — | — | |
| SCHEMBL14863731 | 0.52 | — | — | |
| SCHEMBL3631213 | 0.52 | — | — | |
| Sulfuric Acid SCHEMBL895305 | 0.47 | — | — | |
| Butadiene SCHEMBL21219232 | 0.47 | — | — | |
| Acrolein SCHEMBL21612829 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020115864-A1 | Potentiators of glutamate receptor function | ARNOLD MACKLIN BRIAN (US) | 2002-08-22 | — | — | US | claimed |
| JP-2001511781-A | — | — | 2001-08-14 | — | — | JP | claimed |
| WO-2000006157-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | claimed |
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | claimed |
| US-20040157842-A1 | Sulphonamide derivatives | ARNOLD MACKLIN BRIAN (US) | 2004-08-12 | — | — | US | disclosed |
| US-6713516-B2 | GLUTAMATE RECEPTOR POTENTIATION | ELI LILLY AND COMPANY | 2004-03-30 | — | — | US | disclosed |
| US-20030171350-A1 | Sulphonamide derivatives | ARNOLD MACKLIN BRIAN (US) | 2003-09-11 | — | — | US | disclosed |
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |