SCHEMBL721829

SCHEMBL721829

C=C[CH]NS(N)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767942 0.75
SCHEMBL15561929 0.71
SCHEMBL1040932 0.65
SCHEMBL6750554 0.65
SCHEMBL232503 0.65
SCHEMBL23704655 0.63
SCHEMBL941404 0.63
SCHEMBL943152 0.63
SCHEMBL4894701 0.63
SCHEMBL2880925 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617722-B1 HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT SHIONOGI & CO (JP) 2016-03-23 EP claimed
EP-2834223-A2 (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES Apac Pharmaceutical LLC. (US) 2015-02-11 EP claimed
US-8853248-B2 (1,2,3-triazolyl)sulfonyl derivatives MAEHR HUBERT (US) 2014-10-07 US claimed
US-20130267568-A1 (1,2,3-Triazolyl)sulfonyl Derivatives MAEHR HUBERT (US) 2013-10-10 US claimed
WO-2013151597-A2 (1,2,3-TRIAZOLYL) SULFONYL DERIVATIVES APAC PHARMACEUTICAL LLC. (US) 2013-10-10 WO claimed
US-20120053346-A1 Pyrimidine Carboxamide Derivatives MAEHR HUBERT (US) 2012-03-01 US claimed
EP-3105244-A1 ANTIBACTERIAL AGENTS The University Of Queensland (AU) 2016-12-21 EP disclosed
US-9249107-B2 Pyrimidine carboxamide derivatives MAEHR HUBERT (US) 2016-02-02 US disclosed
WO-2015117196-A1 ANTIBACTERIAL AGENTS THE UNIVERSITY OF QUEENSLAND (AU) 2015-08-13 WO disclosed
US-20150087665-A1 Pyrimidine carboxamide derivatives Maehr, Hubert (US) 2015-03-26 US disclosed