Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.39 |
| ▸ | FEN1 | P39748 | 6/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749847 | 0.90 | F10 (0.59) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6746019 | 0.90 | F10 (0.44) | F10PRSS1F2ALOX5APFEN1 | |
| SCHEMBL6566632 | 0.89 | F10 (0.43) | F10PRSS1F2MMP3 | |
| SCHEMBL6747892 | 0.89 | F10 (0.48) | F10PRSS1F2 | |
| SCHEMBL6746061 | 0.88 | USP30 (0.42) | F10ALOX5APFEN1 | |
| SCHEMBL6565281 | 0.88 | F10 (0.42) | F10PRSS1F2MMP3 | |
| Acetic Acid SCHEMBL6746021 | 0.87 | F10 (0.49) | F10PRSS1F2 | |
| SCHEMBL6749855 | 0.83 | MAPT (0.37) | F10ALOX5APFEN1 | |
| SCHEMBL6564612 | 0.80 | F10 (0.55) | F10PRSS1F2 | |
| SCHEMBL6747940 | 0.79 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | MERCK PATENT GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | F11, F2, F12 | F10 6/4885PRSS1 685/4885F2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.