Cp-96345

Cp-96345

SCHEMBL675160

COc1ccccc1CN[C@H]1[C@H]2CC[N@](CC2)[C@H]1C(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 15/20 1.00
CACNA1F O60840 1/20 1.00
CHRM5 P08912 1/20 1.00
CACNA1D Q01668 1/20 1.00
CACNA1S Q13698 1/20 1.00
CACNA1C Q13936 1/20 1.00
TMEM97 Q5BJF2 1/20 1.00
GPR65 Q8IYL9 1/20 1.00
CYP2D6 P10635 1/20 0.79
NPC1 O15118 1/20 0.70
MTOR P42345 1/20 0.70
RAB9A P51151 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cp-96345 SCHEMBL5419354 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5077901 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL29386897 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5673687 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL1447963 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5419344 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5378537 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL675159 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5419350 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
SCHEMBL9743556 0.95 TACR1 (0.90) TACR1CACNA1FCHRM5CACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6254585-B1 Surgical irrigation solution and method for inhibition of pain and inflammation OMEROS MEDICAL SYSTEMS, INC. 2001-07-03 US claimed
US-20220175797-A1 OPHTHALMOLOGIC IRRIGATION SOLUTIONS AND METHOD OMEROS CORP (US) 2022-06-09 US disclosed
EP-3021856-B1 COMPOSITION FOR INDUCING ORGAN ARREST AND PROTECTION, PRESERVATION AND REDUCTION OF TISSUE INJURY HIBERNATION THERAPEUTICS A KF LLC (US) 2020-10-07 EP disclosed
US-10786525-B2 Method for treating haemorrhage, shock and brain injury HIBERNATION THERAPEUTICS A KF LLC (US) 2020-09-29 US disclosed
US-10251905-B2 Tissue maintenance HIBERNATION THERAPEUTICS, A KF LLC (US) 2019-04-09 US disclosed
US-20170312295-A1 Ophthalmologic Irrigation Solutions and Method OMEROS CORP (US) 2017-11-02 US disclosed
US-20170246150-A1 Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation OMEROS CORPORATION 2017-08-31 US disclosed
US-20170182007-A1 Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation OMEROS CORPORATION 2017-06-29 US disclosed
US-20170100412-A1 OPHTHALMOLOGIC IRRIGATION SOLUTIONS AND METHOD OMEROS CORPORATION 2017-04-13 US disclosed
EP-2079301-B1 IMPROVED TISSUE MAINTENANCE HIBERNATION THERAPEUTICS A KF LLC (US) 2017-03-15 EP disclosed
WO-2000023066-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION OMEROS MEDICAL SYSTEMS, INC. (US) 2000-04-27 WO disclosed
WO-2000023062-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION OMEROS MEDICAL SYSTEMS, INC. (US) 2000-04-27 WO disclosed
US-5860950-A Arthroscopic irrigation solution and method for inhibition of pain and inflammation OMEROS MEDICAL SYSTEMS, INC. (US) 1999-01-19 US disclosed
US-5858017-A Urologic irrigation solution and method for inhibition of pain, inflammation and spasm OMEROS MEDICAL SYSTEMS, INC. (US) 1999-01-12 US disclosed
US-5820583-A DELIVERING TO WOUND DURING SURGERY A DILUTE SOLUTION OF THE SEROTONIN1A, 1B, 1D, 1F RECEPTOR AGONIST SUMATRIPTAN IN A LIQUID CARRIER OMEROS MEDICAL SYSTEMS, INC. (US) 1998-10-13 US disclosed
US-5800385-A Vascular irrigation solution and method for inhibition of pain, inflammation, spasm and restenosis OMEROS MEDICAL SYSTEMS, INC. (US) 1998-09-01 US disclosed
EP-0799051-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN, INFLAMMATION AND SPASM OMEROS MEDICAL SYSTEMS, INC (US) 1997-10-08 EP disclosed
WO-1996019233-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN, INFLAMMATION AND SPASM OMEROS MEDICAL SYSTEMS, INC. (US) 1996-06-27 WO disclosed
EP-0566589-A1 N-ALKYL QUINUCLIDINIUM SALTS AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1993-10-27 EP disclosed
WO-1992012151-A1 N-ALKYL QUINUCLIDINIUM SALTS AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1992-07-23 WO disclosed