Cp-96345

Cp-96345

SCHEMBL675159

COc1ccccc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 15/20 1.00
CACNA1F O60840 1/20 1.00
CHRM5 P08912 1/20 1.00
CACNA1D Q01668 1/20 1.00
CACNA1S Q13698 1/20 1.00
CACNA1C Q13936 1/20 1.00
TMEM97 Q5BJF2 1/20 1.00
GPR65 Q8IYL9 1/20 1.00
CYP2D6 P10635 1/20 0.79
NPC1 O15118 1/20 0.70
MTOR P42345 1/20 0.70
RAB9A P51151 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cp-96345 SCHEMBL5419354 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5077901 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL29386897 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5673687 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL1447963 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5419344 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5378537 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL675160 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
Cp-96345 SCHEMBL5419350 1.00 TACR1 (1.00) TACR1CACNA1FCHRM5CACNA1DCACNA1S
SCHEMBL9743556 0.95 TACR1 (0.90) TACR1CACNA1FCHRM5CACNA1DCACNA1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220288028-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS THE SCHEPENS EYE RESEARCH INSTITUTE, INC. 2022-09-15 US claimed
US-20010006972-A1 NK-1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SYMPTOMS OF IRRITABLE BOWEL SYNDROME WILLIAMS STEPHEN A (US) 2001-07-05 US claimed
US-6254585-B1 Surgical irrigation solution and method for inhibition of pain and inflammation OMEROS MEDICAL SYSTEMS, INC. 2001-07-03 US claimed
EP-0659409-A2 Substance 1 antagonists for the inhibition of angiogenesis PFIZER INC. (US) 1995-06-28 EP claimed
EP-0653208-A2 Pharmaceutical agents for treatment or prevention of sunburn PFIZER INC. (US) 1995-05-17 EP claimed
US-20250186427-A1 METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS UNIVERSITY OF WASHINGTON 2025-06-12 US disclosed
US-20240252484-A1 Methods and Compositions for Treating Vasomotor Symptoms UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2024-08-01 US disclosed
US-20230134843-A1 TREATMENT OF STEM CELL DEFICIENCY OSPEDALE SAN RAFFAELE S.R.L. (IT) 2023-05-04 US disclosed
US-20230134843-A1 TREATMENT OF STEM CELL DEFICIENCY OSPEDALE SAN RAFFAELE S.R.L. (IT) 2023-05-04 US disclosed
US-20220288028-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS THE SCHEPENS EYE RESEARCH INSTITUTE, INC. 2022-09-15 US disclosed
US-20220175797-A1 OPHTHALMOLOGIC IRRIGATION SOLUTIONS AND METHOD OMEROS CORP (US) 2022-06-09 US disclosed
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2022-04-28 US disclosed
EP-0799051-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN, INFLAMMATION AND SPASM OMEROS MEDICAL SYSTEMS, INC (US) 1997-10-08 EP disclosed
WO-1996019233-A2 IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN, INFLAMMATION AND SPASM OMEROS MEDICAL SYSTEMS, INC. (US) 1996-06-27 WO disclosed
EP-0659409-A2 Substance 1 antagonists for the inhibition of angiogenesis PFIZER INC. (US) 1995-06-28 EP disclosed
EP-0653208-A2 Pharmaceutical agents for treatment or prevention of sunburn PFIZER INC. (US) 1995-05-17 EP disclosed
WO-1994004496-A9 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES 1995-01-26 WO disclosed
WO-1994004496-A1 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES PFIZER INC. (US) 1994-03-03 WO disclosed
EP-0566589-A1 N-ALKYL QUINUCLIDINIUM SALTS AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1993-10-27 EP disclosed
WO-1992012151-A1 N-ALKYL QUINUCLIDINIUM SALTS AS SUBSTANCE P ANTAGONISTS PFIZER INC. (US) 1992-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006972-A1 NK-1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SYMPTOMS OF IRRITABLE BOWEL SYNDROME TACR1, TACR2, VIPR1 TACR1 1/4885CACNA1F 779/4885CHRM5 356/4885
US-20240252484-A1 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A TACR1 226/4885CACNA1F 484/4885CHRM5 35/4885
US-20230134843-A1 TREATMENT OF STEM CELL DEFICIENCY KIT, TACR1, MRGPRX2 TACR1 2/4885CACNA1F 1861/4885CHRM5 779/4885
US-20250186427-A1 METHODS AND COMPOSITIONS FOR TREATING VASOMOTOR SYMPTOMS VASP, PDE3A, PDE2A TACR1 226/4885CACNA1F 484/4885CHRM5 35/4885
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A TACR1 226/4885CACNA1F 484/4885CHRM5 35/4885
US-20220288028-A1 A THERAPEUTIC APPROACH FOR TREATING NON-INFECTIOUS OCULAR IMMUNOINFLAMMATORY DISORDERS MSR1, LTB4R2, LTB4R TACR1 12/4885CACNA1F 2535/4885CHRM5 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.