SCHEMBL6751925

SCHEMBL6751925

O=C(O)CCNC(=O)c1ccc(C(NC(=O)Nc2nc3c(F)cc(C(F)(F)F)cc3s2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GCGR P47871 10/20 0.42
PPARD Q03181 1/20 0.42
GIPR P48546 2/20 0.40
GLP1R P43220 1/20 0.40
GCG P01275 8/20 0.40
CSNK1D P48730 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2651825 0.89 GCG (0.43) GCGRPPARDGIPRGLP1RGCG
SCHEMBL2665175 0.87 GCGR (0.47) GCGRPPARDGIPRGLP1RGCG
SCHEMBL2651465 0.87 GCGR (0.41) GCGRPPARDGIPRGLP1RGCG
SCHEMBL6752459 0.85 GCG (0.43) GCGRPPARDGIPRGLP1RGCG
SCHEMBL2651100 0.85 GCGR (0.42) GCGRPPARDGIPRGLP1RGCG
SCHEMBL6752133 0.85 GCGR (0.49) GCGRGIPRGLP1RGCG
SCHEMBL2651441 0.84 GCGR (0.41) GCGRGIPRGLP1RGCG
SCHEMBL2650705 0.84 GCGR (0.42) GCGRPPARDGIPRGLP1RGCG
SCHEMBL6748278 0.84 GCGR (0.41) GCGRPPARDGIPRGLP1RGCG
SCHEMBL2658605 0.84 GCGR (0.52) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706744-B2 HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS NOVO NORDISK A/S (DK) 2004-03-16 US claimed