SCHEMBL6752133

SCHEMBL6752133

O=C(O)CCNC(=O)c1ccc(C(NC(=O)Nc2nc3c(F)cc(C(F)(F)F)cc3s2)c2ccc(C3=CCCCC3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 19/20 0.49
GIPR P48546 13/20 0.49
GLP1R P43220 1/20 0.41
GCG P01275 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6752776 0.89 GCGR (0.52) GCGRGIPRGLP1RGCG
SCHEMBL2665176 0.89 GCGR (0.49) GCGRGIPRGLP1R
SCHEMBL6752763 0.87 GCGR (0.45) GCGRGIPRGLP1R
SCHEMBL2662393 0.86 GCGR (0.49) GCGRGIPRGLP1RGCG
SCHEMBL2651999 0.86 GCGR (0.49) GCGRGIPRGLP1RGCG
SCHEMBL6751925 0.85 GCGR (0.42) GCGRGIPRGLP1RGCG
SCHEMBL2652658 0.85 GCGR (0.59) GCGRGIPRGLP1R
SCHEMBL6752812 0.84 GCGR (0.43) GCGRGIPRGLP1RGCG
SCHEMBL6752813 0.84 GCGR (0.50) GCGRGIPRGLP1R
SCHEMBL2651914 0.84 GCGR (0.46) GCGRGIPRGLP1RGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706744-B2 HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS NOVO NORDISK A/S (DK) 2004-03-16 US claimed