Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CD44 | P16070 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12657972 | 0.76 | PARP1 (0.44) | PARP1ALDH1A1L3MBTL1BRD4CD44 | |
| SCHEMBL14431629 | 0.76 | BCL2L1 (0.48) | PARP1ALDH1A1BRD4ADRA2AHSD17B10 | |
| SCHEMBL2768935 | 0.76 | PARP1 (0.53) | PARP1ALDH1A1L3MBTL1BRD4HSD17B10 | |
| SCHEMBL13625677 | 0.72 | PARP1 (0.38) | PARP1ALDH1A1BRD4CD44KDM4E | |
| SCHEMBL14128548 | 0.72 | ABCB1 (0.47) | BRD4KDM4ELMNAMAPT | |
| SCHEMBL12288819 | 0.72 | PARP1 (0.41) | PARP1ALDH1A1L3MBTL1BRD4CD44 | |
| Formamide SCHEMBL6754148 | 0.71 | PARP1 (0.47) | PARP1BRD4HSD17B10HPGDTSHR | |
| Urea SCHEMBL6754151 | 0.71 | BRD4 (0.48) | PARP1ALDH1A1BRD4TSHRPTPRC | |
| SCHEMBL353635 | 0.70 | CD44 (0.53) | PARP1ALDH1A1CD44ADRA2AHSD17B10 | |
| SCHEMBL29661353 | 0.70 | CD44 (0.53) | PARP1ALDH1A1CD44ADRA2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | claimed |
| CN-1275934-C | Process for the production of 1, 5-naphthalenediamine | BAYER AG (DE) | 2006-09-20 | — | — | CN | disclosed |
| CN-1483017-A | Process for the production of 1, 5-naphthalenediamine | 拜尔公司 | 2004-03-17 | — | — | CN | disclosed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| US-6706924-B2 | INCLUDES A STEP IN WHICH ORTHO-NITROTOLUENE IS REACTED WITH ONE OR MORE ACRYLIC ACID DERIVATIVES SUCH AS ACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | disclosed |
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-01 | — | — | US | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103401-A1 | Process for the production of 1,5-naphthalenediamine | BBOX1, CYP4B1, NAT1 | PARP1 1388/4885ALDH1A1 455/4885L3MBTL1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.