SCHEMBL6752160

SCHEMBL6752160

Brc1c2ccccc2c2c3cccc4c(Br)c5ccccc5c(c5cccc1c52)c43

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CYP1A2 P05177 5/20 0.42
HSD17B10 Q99714 3/20 0.42
HPGD P15428 2/20 0.42
THRB P10828 1/20 0.42
POLB P06746 1/20 0.34
TSHR P16473 2/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
CYP2C19 P33261 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6753590 0.94 ALDH1A1 (0.42) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL6078517 0.91 ALDH1A1 (0.52) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL31502573 0.89 CYP1A2 (0.42) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL31502572 0.89 CYP1A2 (0.42) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL6753573 0.83 CYP1A2 (0.55) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL19067196 0.82 CYP1A2 (0.36) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL12014663 0.82 HSD17B10 (0.60) ALDH1A1CYP1A2HSD17B10HPGDTHRB
SCHEMBL28511 0.82 ALDH1A1 (0.44) ALDH1A1CYP1A2HSD17B10POLBTSHR
SCHEMBL29352635 0.82 ALDH1A1 (0.44) ALDH1A1CYP1A2HSD17B10POLBTSHR
SCHEMBL13483302 0.80 CYP1A2 (0.37) ALDH1A1CYP1A2HSD17B10HPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6746784-B2 SUBSTITUTED OR UNSUBSTITUTED CYCLOHEXYLIDENEMETHINE GROUP COMPOUNDS WITH IMPROVED HOLE INJECTION PROPERTIES SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-06-08 US disclosed
US-6699594-B1 Organic electroluminescent device NEC CORPORATION (JP) 2004-03-02 US disclosed
US-6465116-B1 8-(N-4-(4-METHYLPHENYLVINYL)PHENYL-N-P-TOLYLAMINO)-16-(N-PHENYL-N-P -TOLYLA MINO)DIBENZO(A,J)PERYLENE THIN FILMS BETWEEN ANODES AND CATHODES, HAVING BRIGHTNESS AND DURABILITY NEC CORPORATION (JP) 2002-10-15 US disclosed
US-20020058156-A1 Substituted or unsubstituted cyclohexylidenemethine group compounds with improved hole injection properties SAMSUNG DISPLAY CO., LTD. (KR) 2002-05-16 US disclosed