Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.49 |
| ▸ | F10 | P00742 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644146 | 0.88 | PTGS2 (0.69) | PTGS2PTGS1F10F2 | |
| SCHEMBL4027958 | 0.83 | PTGS2 (0.65) | PTGS2PTGS1RXRANR1H2NR1H3 | |
| SCHEMBL8639888 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1F10F2 | |
| SCHEMBL8639809 | 0.79 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8765410 | 0.79 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL6164598 | 0.78 | PTGS1 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8640826 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8638143 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8639295 | 0.78 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL8641753 | 0.78 | PTGS2 (0.56) | PTGS2PTGS1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020028798-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS MEDICAL SYSTEMS | 2002-03-07 | — | — | US | claimed |
| WO-2000023061-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | OMEROS MEDICAL SYSTEMS, INC. (US) | 2000-04-27 | — | — | WO | claimed |
| US-20170246150-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2017-08-31 | — | — | US | disclosed |
| US-20170182007-A1 | Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation | OMEROS CORPORATION | 2017-06-29 | — | — | US | disclosed |
| US-20160184272-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2016-06-30 | — | — | US | disclosed |
| US-20160120846-A1 | Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation | OMEROS CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-20160067219-A1 | Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation | OMEROS CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-9254271-B2 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION (US) | 2016-02-09 | — | — | US | disclosed |
| US-20130324475-A1 | Arthroscopic Irrigation Solution and Method for Peripheral Vasoconstriction and Inhibition of Pain and Inflammation | OMEROS CORPORATION (US) | 2013-12-05 | — | — | US | disclosed |
| US-8450309-B2 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION (US) | 2013-05-28 | — | — | US | disclosed |
| US-20120310140-A1 | DIRECTED DELIVERY OF AGENTS TO NEURAL ANATOMY | SPINAL MODULATION, INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-6713463-B2 | Methods and compositions for treating and preventing mucositis | MUCOSAL THERAPEUTICS, LLC | 2004-03-30 | — | — | US | disclosed |
| WO-2004000223-A2 | RAPIDLY DISINTEGRATING FORMULATIONS FOR TREATING OR PREVENTING MUCOSITIS | ORAPHARMA, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030096807-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2003-05-22 | — | — | US | disclosed |
| US-20030087962-A1 | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation | OMEROS CORPORATION | 2003-05-08 | — | — | US | disclosed |
| US-20030036560-A1 | Methods and compositions for treating and preventing mucositis | MUCOSAL THERAPEUTICS LLC | 2003-02-20 | — | — | US | disclosed |
| US-6458777-B1 | Methods and compositions for treating and preventing mucositis | MUCOSAL THERAPEUTICS LLC | 2002-10-01 | — | — | US | disclosed |
| US-20020028798-A1 | Irrigation solution and method for inhibition of pain and inflammation | OMEROS MEDICAL SYSTEMS | 2002-03-07 | — | — | US | disclosed |
| US-20010011097-A1 | Methods and compositions for treating and preventing mucositis | VENTURE LENDING & LEASING IV, INC. | 2001-08-02 | — | — | US | disclosed |
| WO-2000023061-A2 | IRRIGATION SOLUTION AND METHOD FOR INHIBITION OF PAIN AND INFLAMMATION | OMEROS MEDICAL SYSTEMS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |