SCHEMBL675255

SCHEMBL675255

CC(C)(c1ccccc1)c1cc(Cc2cc(C(C)(C)c3ccccc3)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
LMNA P02545 1/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 4/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CYP3A4 P08684 2/20 0.38
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
ALOX15 P16050 2/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 4/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
HPGD P15428 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31079418 1.00 NPC1 (0.44) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL31267653 1.00 NPC1 (0.44) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL14323123 0.94 NPC1 (0.41) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL11346033 0.89 NPC1 (0.38) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL699155 0.88 NPC1 (0.47) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL9868106 0.87 NPC1 (0.40) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL2380314 0.85 NPC1 (0.45) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL7701678 0.85 NPC1 (0.47) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL8861285 0.85 NPC1 (0.50) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL14324434 0.84 MEN1 (0.40) NPC1RAB9APOLBCYP3A4CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4628540-A1 RESIN COMPOSITION, PELLETS AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2025-10-08 EP disclosed
EP-4628541-A1 RESIN COMPOSITION, PELLET, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2025-10-08 EP disclosed
US-20250282949-A1 RESIN COMPOSITION, PELLET, AND FORMED ARTICLE MITSUBISHI CHEMICAL CORPORATION (JP) 2025-09-11 US disclosed
US-20250282948-A1 RESIN COMPOSITION, PELLET, FORMED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2025-09-11 US disclosed
EP-4574907-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2025-06-25 EP disclosed
EP-4520793-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2025-03-12 EP disclosed
US-20250051564-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2025-02-13 US disclosed
WO-2024038853-A1 RESIN COMPOSITION, PELLETS, AND MOLDED ARTICLE 三菱ケミカル株式会社 2024-02-22 WO disclosed
WO-2023214487-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING RESIN COMPOSITION 三菱ケミカル株式会社 2023-11-09 WO disclosed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 US disclosed
EP-1892266-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES MITSUBISHI ENG PLASTICS CORP (JP) 2010-07-21 EP disclosed
US-20090186967-A1 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) 2009-07-23 US disclosed
EP-1892266-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES Mitsubishi Engineering-Plastics Corporation (JP) 2008-02-27 EP disclosed
US-6762250-B2 TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-07-13 US disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
US-20040054116-A1 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-03-18 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed