Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861285 | 0.89 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29903 | 0.87 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL29354035 | 0.87 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL7574172 | 0.87 | NPC1 (0.50) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL6558920 | 0.86 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30393631 | 0.86 | NPC1 (0.45) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL675255 | 0.85 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL31267653 | 0.85 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL31079418 | 0.85 | NPC1 (0.44) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL1264046 | 0.83 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344505-B1 | Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers | CYTEC INDUSTRIES INC. | 2002-02-05 | — | — | US | disclosed |