SCHEMBL6753271

SCHEMBL6753271

N[C@@H](Cc1ccc(N2CCOCC2)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.54
ACACB O00763 1/20 0.53
PTGS1 P23219 3/20 0.53
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
XIAP P98170 1/20 0.53
TPH1 P17752 3/20 0.52
SLC13A5 Q86YT5 1/20 0.48
GSK3B P49841 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TYR P14679 5/20 0.47
GRB2 P62993 1/20 0.47
ALOX15 P16050 2/20 0.46
HIF1A Q16665 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
EGFR P00533 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024981 1.00 SLC7A5 (0.54) SLC7A5ACACBPTGS1ALPIPKM
SCHEMBL28706525 1.00 SLC7A5 (0.54) SLC7A5ACACBPTGS1ALPIPKM
SCHEMBL16861052 0.91 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL18280216 0.91 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2779534 0.88 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2779539 0.88 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL6776426 0.86 SLC7A5 (0.56) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL6776419 0.86 SLC7A5 (0.56) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL31627474 0.86 KMT2A (0.59) SLC7A5PKMSMN1; SMN2ALOX15TDP1
SCHEMBL34468308 0.86 KMT2A (0.59) SLC7A5PKMSMN1; SMN2ALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720087-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2026-04-08 EP disclosed
WO-2024246269-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2024-12-05 WO disclosed
EP-2599484-A1 INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN Eriochem, S.A. (AR) 2013-06-05 EP disclosed
US-20130131174-A1 INJECTABLE PHARMACEUTICAL FORMULATION OF MELPHALAN ERIOCHEM (AR) 2013-05-23 US disclosed
US-6759428-B2 SUCH AS N-((1,2)-2-(((CYANO(CYCLOPROPYL)METHYL)AMINO)CARBONYL) CYCLOHEXYL)-1H-INDOLE-2-CARBOXAMIDE; CATHEPSIN K INHIBITORS ROCHE PALO ALTO LLC 2004-07-06 US disclosed
US-20040077646-A1 Indole nitriles ROCHE PALO ALTO LLC 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077646-A1 Indole nitriles TPH1, IDO1, NAT1 SLC7A5 1553/4885ACACB 3595/4885PTGS1 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.