Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.46 |
| ▸ | HMGCR | P04035 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27216011 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8410683 | 0.97 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL28214293 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8413428 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL21484045 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8412547 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL10886003 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL8413427 | 0.92 | TSHR (0.68) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL11067391 | 0.92 | TSHR (0.56) | TSHRALDH1A1TDP1PTPN7HMGCR | |
| SCHEMBL3317342 | 0.86 | TSHR (0.60) | TSHRALDH1A1TDP1PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56073033-A | — | — | None | — | — | JP | disclosed |
| CN-107884493-B | Method for analyzing short-chain chlorinated paraffin in environmental sample by using full-two-dimensional gas chromatography-time-of-flight mass spectrometry | 国家地质实验测试中心 | 2020-11-24 | — | — | CN | disclosed |
| EP-1233669-B1 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-1233669-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6365549-B2 | PRESERVATION | NORTH CAROLINA STATE UNIVERSITY | 2002-04-02 | — | — | US | disclosed |
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | NORTH CAROLINA STATE UNIVERSITY | 2001-09-06 | — | — | US | disclosed |
| WO-2001037663-A2 | BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-0084860-A1 | A novel compound 5-chloro-1-bromo-1-pentyne and a method for the preparation thereof | Shin-Etsu Chemical Co., Ltd. (JP) | 1983-08-03 | — | — | EP | disclosed |
| JP-S5673033-A | 1-HALO-4-DECYNE COMPOUND | SHIN ETSU CHEM CO LTD | 1981-06-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019995-A1 | Methods of blocking an ethylene response in plants using cyclopropene derivatives | PRUNE1, NOTUM, FAR1 | TSHR 2454/4885ALDH1A1 3933/4885TDP1 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.