SCHEMBL6753907

SCHEMBL6753907

O=C(Nc1ccccc1)C(F)C(=O)C(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
MAPT P10636 5/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 3/20 0.49
GAA P10253 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ATM Q13315 2/20 0.49
LMNA P02545 2/20 0.49
RXFP1 Q9HBX9 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
TP53 P04637 1/20 0.48
EPHX1 P07099 1/20 0.48
TSHR P16473 1/20 0.48
EPHX2 P34913 1/20 0.48
CDK9 P50750 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
HSP90AA1 P07900 2/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1703604 0.84 POLB (0.61) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL11381083 0.81 MAPT (0.62) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL31054221 0.77 SMN1; SMN2 (0.65) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL27218362 0.77 POLB (0.49) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL9676988 0.76 POLB (0.57) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL10435602 0.76 MAPT (0.61) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL7939406 0.76 MEN1 (0.61) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL29077383 0.76 POLB (0.57) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL17968494 0.74 POLB (0.66) POLBMAPTMEN1KMT2AALDH1A1
SCHEMBL225217 0.74 TAAR1 (0.60) POLBMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146151-A 4-Trifluoromethyl substituted quinoline and quinazoline compound and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2024-06-07 CN disclosed
US-6749908-B2 LAMINATES/TRANSPARENCIES FOR OVERHEAD PROJECTORS FUJI PHOTO FILM CO., LTD. (JP) 2004-06-15 US disclosed
US-20030138720-A1 Multicolor heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-07-24 US disclosed
US-20030114305-A1 Multicolor heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-06-19 US disclosed
US-6017672-A MIXTURE OF DIAZONIUM SALT HAVING ABSORPTION WAVELENGTH SHORTER THAN 350 NANOMETERS AND A THERMALLY REACTIVE COUPLER CONTAINED WITHIN RECORDING LAYER COATED ONTO SUPPORT; STORAGE STABILITY, PHOTOSTABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO., LTD. (JP) 2000-01-25 US disclosed
WO-1995032952-A1 PROCESS FOR THE PREPARATION OF 3-ARYLURACILS CIBA-GEIGY AG (CH) 1995-12-07 WO disclosed