Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703604 | 0.83 | POLB (0.61) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL4296111 | 0.83 | MAPT (0.85) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL6977552 | 0.82 | ALDH1A1 (0.53) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL9676988 | 0.79 | POLB (0.57) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL9518770 | 0.79 | MAPT (0.72) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL29077383 | 0.79 | POLB (0.57) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL11758471 | 0.79 | MAPT (0.61) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL11174713 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL10948584 | 0.79 | MAPT (0.61) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL998876 | 0.79 | MAPT (0.61) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138657-A1 | Process for generating electrophiles from anions by reaction with electrophilic fluorinating agent | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6270843-B1 | REACTING A SALT COMPRISING ANIONIC FORM OF SUBSTITUENT WITH AN ELECTROPHILIC FLUORINATION AGENT TO PROVIDE AN ELECTROPHILE COMPRISING CATIONIC FORM OF SUBSTITUENT; ELECTROPHILICALLY SUBSTITUTING ELECTROPHILE ON SUBSTRATE | AIR PRODUCTS AND CHEMICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| US-4175948-A | HERBICIDES, POSTMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-27 | — | — | US | disclosed |
| US-4123252-A | Methoxy substituted cycloalkanapyrazole herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4120693-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4111681-A | CYCLOALKANAPYRAZOLE-3-CARBONITRILE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4108628-A | Cycloalkanopyrazole herbicides mixtures | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4059434-A | Cycloalkanapyrazole herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4042373-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4033751-A | 2-(Substituted-phenyl)-hexahydro- and tetrahydro-3-(2H)-cinnolinones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4032326-A | HERBICIDAL 2-SUBSTITUTED ARYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4003926-A | Herbicidal 2-arylaminocarbonyl-1-cyclohexene-1-carboxylic acids and salts thereof | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
| US-4001272-A | HERBICIDAL 2-FLUORO-4-HALO-PHENYL-4,5,6,7-TETRAHYDRO-2H-ISOINDOLE-1,3-DIONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3990880-A | Herbicidal isobenzofuranones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3987057-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |