4-Aminophenol

4-Aminophenol

SCHEMBL6753971

Nc1ccc(N)cc1.Nc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
CYP3A4 P08684 3/20 1.00
ALOX15 P16050 3/20 1.00
CA3 P07451 2/20 1.00
HIF1A Q16665 2/20 1.00
HSD17B10 Q99714 2/20 1.00
CA14 Q9ULX7 2/20 1.00
THRB P10828 2/20 1.00
CA6 P23280 1/20 1.00
CASP1 P29466 1/20 1.00
APP P05067 3/20 0.68
KMT2A Q03164 3/20 0.61
MAPT P10636 3/20 0.61
KDM4E B2RXH2 3/20 0.61
BLM P54132 3/20 0.61
MEN1 O00255 2/20 0.61
NPC1 O15118 1/20 0.61
CA12 O43570 1/20 0.61
GMNN O75496 1/20 0.61
CA1 P00915 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Aminophenol SCHEMBL3424 1.00
4-Aminophenol SCHEMBL4861305 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL3887333 0.96
4-Aminophenol SCHEMBL3887275 0.96
4-Aminophenol SCHEMBL6933462 0.96 ALDH1A1 (0.93) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL1435122 0.96 ALDH1A1 (0.93) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL1886379 0.96
4-Aminophenol SCHEMBL19972054 0.96
4-Aminophenol SCHEMBL6788952 0.96
4-Aminophenol SCHEMBL3897816 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6342078-B1 OXIDATION COLOR DYES FOR HAIR WITH METAPHENYLENEDIAMINE COUPLERS L'OREAL, S. A. (FR) 2002-01-29 US claimed
CN-105853246-B Keratin dyeing compositions and application thereof comprising free radical scavenger and chelating agent 诺赛尔股份有限公司 2019-07-26 CN disclosed
CN-103589530-B Delivery of particles 宝洁公司 2016-08-24 CN disclosed
CN-102249043-A Reversible cover type double-compartment tubular container and manufacturing method thereof HYEON-MIN SHIN 2011-11-23 CN disclosed
CN-1205180-C 3- (2, 5-diaminophenyl) -acrylamide derivatives and coloring agents containing said compounds P & G CLAROLL CORP (US) 2005-06-08 CN disclosed
US-20040197714-A1 Method of silvery recovery from color photographic processing EASTMAN KODAK COMPANY 2004-10-07 US disclosed
CN-1443154-A 3- (2, 5-diaminophenyl) -acrylamide derivatives and coloring agents containing said compounds WELLA AG (DE) 2003-09-17 CN disclosed
CN-1137375-A Composition for oxidation dyeing of keratin fibres, comprising at least two oxidation bases and dation be coupler, and dyeing process OREAL (FR) 1996-12-11 CN disclosed
US-5480459-A Oxidative hair dye based on a creamlike carrier composition as well as process for the dyeing of hair WELLA AKTIENGESELLSCHAFT (DE) 1996-01-02 US disclosed