Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924977 | 0.89 | DHODH (0.63) | DHODHNR4A2FABP4FABP5MEN1 | |
| SCHEMBL6813881 | 0.82 | DHODH (0.65) | DHODHNR4A2FABP4FABP5 | |
| SCHEMBL6754645 | 0.80 | DHODH (0.65) | DHODHNR4A2 | |
| SCHEMBL3919682 | 0.79 | DHODH (0.73) | DHODHNR4A2 | |
| SCHEMBL251960 | 0.78 | DHODH (0.79) | DHODHNR4A2 | |
| SCHEMBL3916865 | 0.78 | P4HTM (0.59) | DHODH | |
| SCHEMBL249278 | 0.78 | DHODH (0.69) | DHODHNR4A2FABP4FABP5 | |
| SCHEMBL6859682 | 0.78 | DHODH (0.64) | DHODHNR4A2 | |
| SCHEMBL6814538 | 0.77 | DHODH (0.53) | DHODHNR4A2FABP4FABP5 | |
| SCHEMBL248162 | 0.77 | DHODH (0.62) | DHODHNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392642-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003006425-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2003-01-23 | — | — | WO | disclosed |