Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.55 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252179 | 0.87 | DHODH (0.83) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL3916865 | 0.86 | P4HTM (0.59) | DHODH | |
| SCHEMBL502900 | 0.85 | DHODH (0.83) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6756245 | 0.82 | DHODH (0.68) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL3926145 | 0.82 | DHODH (0.82) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL248162 | 0.81 | DHODH (0.62) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL254247 | 0.80 | DHODH (0.84) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL6754115 | 0.80 | DHODH (0.60) | DHODHNR4A2 | |
| SCHEMBL3918103 | 0.79 | DHODH (0.61) | DHODHNR4A2NR4A1JMJD7NR4A3 | |
| SCHEMBL3919682 | 0.79 | DHODH (0.73) | DHODHNR4A2NR4A1JMJD7NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392642-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003006425-A9 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-02-26 | — | — | WO | disclosed |
| WO-2003006425-A2 | NOVEL COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2003-01-23 | — | — | WO | disclosed |