Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073109 | 0.81 | HPGD (0.37) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL29098855 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2749161 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Fluoride SCHEMBL28542369 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL13113538 | 0.68 | MEN1 (0.50) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL13113547 | 0.68 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL30551682 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL27942734 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL4467765 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| Thioxanthene SCHEMBL29398766 | 0.65 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485377-A1 | PYRANONES USEFUL AS ATM INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070726-A1 | PYRANONES USEFUL AS ATM INHIBITORS | KUDOS PHARMACEUTICALS LTD (GB) | 2003-08-28 | — | — | WO | disclosed |