Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304075 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL6306816 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL18519947 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL6756565 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL6513254 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL18519944 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TSHRNPC1KMT2ARAB9A | |
| SCHEMBL22216702 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1KMT2ARAB9ACHRNB2 | |
| SCHEMBL21877952 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ACHRNB2 | |
| SCHEMBL25997355 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ACHRNB2 | |
| SCHEMBL18490597 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRNPC1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478322-A2 | Beta-2'-OR 3'-HALONUCLEOSIDES | Pharmasset Limited (BB) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003000200-A2 | β-2'-OR 3'-HALONUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-01-03 | — | — | WO | disclosed |