Adamantane

Adamantane

SCHEMBL6754658

C1C2CC3CC1C1C(C2)C31.C1C2CC3CC1CC(C2)C3

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.40
HSD11B1 P28845 1/20 0.35
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2189873 0.78 CYP2C9 (0.50) CYP2C9HSD11B1EPHX2
Adamantane SCHEMBL8979787 0.69 CYP2C9 (0.38) CYP2C9
Adamantane SCHEMBL19350269 0.68 CYP2C9 (0.43) CYP2C9EPHX2
SCHEMBL24917452 0.67
SCHEMBL20579816 0.67 CYP2C9 (0.33) CYP2C9
Hydrogen Peroxide SCHEMBL28741420 0.65 CYP2C9 (0.35) CYP2C9HSD11B1
SCHEMBL9427059 0.65 CYP2C9 (0.32) CYP2C9
SCHEMBL17762984 0.65 CYP2C9 (0.32) CYP2C9
SCHEMBL7042809 0.65 CYP2C9 (0.32) CYP2C9
SCHEMBL546128 0.65 CYP2C9 (0.61) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425316-A2 LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES Honeywell International, Inc. (US) 2004-06-09 EP disclosed
WO-2003007337-A2 LOW DIELECTRIC CONSTANT ORGANIC DIELECTRICS BASED ON CAGE-LIKE STRUCTURES HONEYWELL INTERNATIONAL INC. (US) 2003-01-23 WO disclosed