Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752091 | 0.83 | KDM4E (0.54) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL17312023 | 0.83 | KDM4E (0.49) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL6618712 | 0.83 | KDM4E (0.49) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL11211578 | 0.80 | ERN1 (0.53) | KDM4EMAPTGAATRPM4ERN1 | |
| SCHEMBL13666895 | 0.79 | KDM4E (0.62) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL5675873 | 0.78 | KDM4E (0.54) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL8582319 | 0.77 | KDM4E (0.59) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL27367553 | 0.76 | KDM4E (0.53) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL8782851 | 0.76 | MAPT (0.49) | KDM4EMAPTGAAHTTHSD17B10 | |
| SCHEMBL9713872 | 0.75 | KDM4E (0.59) | KDM4EMAPTGAAHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716257-B2 | OXIDATION DYES, WHICH ARE USED FOR TREATMENT OF HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1236460-A1 | Bridged diamino pyrazoles and colouring agents containing them | Wella Aktiengesellschaft (DE) | 2002-09-04 | — | — | EP | disclosed |