Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755866 | 0.83 | KDM4E (0.58) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL4752091 | 0.81 | KDM4E (0.54) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL17312023 | 0.81 | KDM4E (0.49) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL8107317 | 0.81 | KDM4E (0.50) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL6621295 | 0.79 | HPGD (0.46) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL13666895 | 0.77 | KDM4E (0.62) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL6620676 | 0.77 | MAPT (0.51) | KDM4EMAPTALDH1A1HPGDMAOB | |
| SCHEMBL8582319 | 0.76 | KDM4E (0.59) | KDM4EMAPTHTTHSD17B10GAA | |
| SCHEMBL6623814 | 0.76 | ALDH1A1 (0.45) | KDM4EMAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL27367553 | 0.75 | KDM4E (0.53) | KDM4EMAPTHTTHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |