SCHEMBL6756161

SCHEMBL6756161

Nc1cc(C(=O)c2ccc(S)c(N)c2)ccc1S

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
GAA P10253 3/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPK1 P28482 2/20 0.52
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
HTT P42858 2/20 0.52
NPC1 O15118 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HSD17B10 Q99714 2/20 0.47
USP2 O75604 1/20 0.47
RAB9A P51151 1/20 0.47
TUBB4A P04350 1/20 0.43
TUBB P07437 1/20 0.43
TUBA3C P0DPH7 1/20 0.43
TUBA1B P68363 1/20 0.43
TUBA4A P68366 1/20 0.43
TUBB4B P68371 1/20 0.43
TUBB3 Q13509 1/20 0.43
TUBB2A Q13885 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2318456 0.86 CDC25B (0.52) MAPTGAAALDH1A1LMNAL3MBTL1
Hydrochloric Acid SCHEMBL5476894 0.84 CDC25B (0.50) MAPTGAAALDH1A1LMNAL3MBTL1
SCHEMBL6516193 0.84 CDC25B (0.50) MAPTGAAALDH1A1LMNAL3MBTL1
SCHEMBL6513019 0.84 CDC25B (0.50) MAPTGAAALDH1A1LMNAL3MBTL1
SCHEMBL6513011 0.84 CDC25B (0.50) MAPTGAAALDH1A1LMNAL3MBTL1
SCHEMBL6511407 0.84 ALDH1A1 (0.45) MAPTALDH1A1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL6515993 0.83 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL6515986 0.83 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL6515621 0.83 MAPT (0.39) MAPTGAAALDH1A1MAPK1LMNA
SCHEMBL6515960 0.83 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120135251-A1 PHOTOSENSITIVE POLYIMIDE HAVING SILICON MODIFIED GROUP, ADHESIVE COMPOSITION AND SEMICONDUCTOR PACKAGE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-31 US disclosed
US-20040152862-A1 Optical resins and applications thereof HITACHI CHEMICAL CO., LTD. (JP) 2004-08-05 US disclosed
CN-1474844-A Polybenzole compound having sulfo group and/or phosphono group, resin composition containing same, molded resin, solid polymer electrotyte film, solid electrolyte film/electrode catalyst layer ... �����֯��ʽ���� 2004-02-11 CN disclosed