Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056183 | 0.83 | GAA (0.54) | GAADDAH1POLBNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL20677811 | 0.81 | NPSR1 (0.54) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL4562346 | 0.79 | DDAH1 (0.59) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL4124111 | 0.79 | DDAH1 (0.65) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL2277460 | 0.79 | DDAH1 (0.59) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL30679038 | 0.79 | DDAH1 (0.59) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL23301149 | 0.78 | DDAH1 (0.54) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL4963917 | 0.78 | MAPT (0.51) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL4619198 | 0.76 | DDAH1 (0.61) | GAADDAH1POLBNPC1RAB9A | |
| SCHEMBL10761755 | 0.76 | DDAH1 (0.61) | GAADDAH1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |