Styrene

Styrene

SCHEMBL6756264

C=C(C=C(C)C(=O)O)C(=O)OCCCC.C=CC(=O)OC.C=Cc1ccccc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
TSHR P16473 5/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 3/20 0.38
KMT2A Q03164 3/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
THRB P10828 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
THRA P10827 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL251772 0.92 KDM4E (0.45) KDM4ETSHRHPGDTDP1KMT2A
Styrene SCHEMBL4627611 0.91 KDM4E (0.43) KDM4ETSHRHPGDTDP1KMT2A
Styrene SCHEMBL461109 0.91 KDM4E (0.43) KDM4ETSHRTDP1KMT2APOLB
Styrene SCHEMBL8097084 0.88 TSHR (0.46) KDM4ETSHRTDP1POLBL3MBTL1
Styrene SCHEMBL1085643 0.86 KDM4E (0.41) KDM4ETSHRHPGDTDP1KMT2A
Styrene SCHEMBL8022945 0.86 KDM4E (0.38) KDM4ETSHRHPGDTDP1KMT2A
Styrene SCHEMBL5947075 0.85 TSHR (0.41) KDM4ETSHRHPGDTDP1KMT2A
Acrylic Acid Ethyl Ester SCHEMBL8607717 0.85 TSHR (0.49) KDM4ETSHRHPGDTHRBRAB9A
Styrene SCHEMBL8320874 0.85 TSHR (0.37) KDM4ETSHRHPGDTDP1KMT2A
Styrene SCHEMBL11390360 0.84 KDM4E (0.39) KDM4ETSHRHPGDTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6701842-B2 Process for the treatment of an erasable lithographic printing plate MAN ROLAND DRUCKMASCHINEN AG (DE) 2004-03-09 US disclosed
US-6677010-B1 SUBSTRATE MUST FULFILL MECHANICAL REQUIREMENTS DURING TRANSFER, OPTICAL REQUIREMENTS OF THE LIGHT TRANSMISSION WHEN IRRADIATED WITH A LASER BEAM AND THERMAL REQUIREMENTS OF HEATING OF THE COATED LAYER MAN ROLAND DRUCKMASCHINEN AG (DE) 2004-01-13 US disclosed
US-6638669-B2 For imaging a lithographic printing-plate cylinder, for offset printing, by laser-induced transfer MAN ROLAND DRUCKMASCHINEN AG (DE) 2003-10-28 US disclosed
US-20020096074-A1 Process for the treatment of an erasable lithographic printing plate MAN ROLAND DRUCKMASCHINEN AG 2002-07-25 US disclosed
US-20020064717-A1 Thermal transfer film comprising a reactive polymer composition for laser-induced coating MAN ROLAND DRUCKMASCHINEN AG 2002-05-30 US disclosed