Styrene

Styrene

SCHEMBL8022945

C=C(C)C(=O)OC.C=C(C)C(=O)OCC(C)O.C=C(C=C(C)C(=O)O)C(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
TSHR P16473 5/20 0.36
TDP1 Q9NUW8 3/20 0.36
POLB P06746 4/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL461109 0.92 KDM4E (0.43) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL8320874 0.88 TSHR (0.37) KDM4ETSHRTDP1POLBKMT2A
Styrene SCHEMBL251772 0.86 KDM4E (0.45) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL6756264 0.86 KDM4E (0.42) KDM4ETSHRTDP1POLBKMT2A
Styrene SCHEMBL5947075 0.86 TSHR (0.41) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL4627611 0.85 KDM4E (0.43) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL193968 0.84 TSHR (0.48) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL4210153 0.84 TSHR (0.50) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL10906558 0.83 TSHR (0.48) KDM4ETSHRTDP1POLBAPEX1
Styrene SCHEMBL8586039 0.83 TSHR (0.47) KDM4ETSHRTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695783-B1 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR (JP) 2000-02-02 EP disclosed
US-5650475-A VINYL POLYMERS WITH BLOCKED CARBOXY, SILANOL, EPOXY, HYDROLYZED SILYL AND ACID ANHYDRIDES IN SOLVENTS MAZDA MOTOR CORPORATION (JP) 1997-07-22 US disclosed
EP-0695783-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition Mazda Motor Corporation (JP) 1996-02-07 EP disclosed