Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756333 | 0.85 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL6757261 | 0.85 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL3355959 | 0.83 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL3355674 | 0.83 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL5618922 | 0.81 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL19435433 | 0.80 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL3352351 | 0.80 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL6759213 | 0.80 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL3355143 | 0.80 | TLR7 (0.54) | TLR7TLR8 | |
| SCHEMBL3350923 | 0.80 | TLR7 (0.50) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204436-A1 | Imidazonaphthyridines | MEDICIS PHARMACEUTICAL CORPORATION | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204436-A1 | Imidazonaphthyridines | IFNG, IRF3, IFNAR1 | TLR7 109/4885TLR8 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.