Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 2/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947121 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29947100 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29947066 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29947125 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29947102 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29519837 | 0.94 | GNPAT (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL31521782 | 0.93 | NPY4R (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29519789 | 0.93 | NPY4R (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL29395932 | 0.93 | NPY4R (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL27547048 | 0.93 | GNPAT (0.44) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060739-B1 | Slimming cosmetic composition containing L-arginine or a derivative thereof | EXSYMOL SA (MC) | 2013-04-03 | — | — | EP | disclosed |
| US-6716436-B1 | IN COMBINATION WITH COSMETICALLY ACCEPTABLE EXCIPIENT AT LEAST ONE NITRIC OXIDE PRECURSOR COMPOUND WHICH IS L-ARGININE ANALOGUE OR ONE OF ITS DERIVATIVES OR SALTS | EXSYMOL S.A.M. (MC) | 2004-04-06 | — | — | US | disclosed |
| EP-1060739-A1 | Slimming cosmetic composition containing L-arginine or a derivative thereof | EXSYMOL S.A.M. (MC) | 2000-12-20 | — | — | EP | disclosed |