Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756743 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL6756829 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL6757787 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL19214262 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL22143673 | 0.73 | MKNK1 (0.52) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL6754277 | 0.69 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL6757847 | 0.66 | ALDH1A1 (0.46) | ALDH1A1MKNK1MKNK2HCAR1FGFR1 | |
| SCHEMBL30899602 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL29205263 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A | |
| SCHEMBL9288138 | 0.65 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP1A2CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | ALDH1A1 1144/4885HPGD 1663/4885CYP1A2 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.