SCHEMBL67572

SCHEMBL67572

Oc1c(Cl)cc(Cl)c(Cc2c(Cl)cc(Cl)c(O)c2Cl)c1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.67
TSHR P16473 5/20 0.67
HPGD P15428 5/20 0.67
CYP3A4 P08684 5/20 0.67
HIF1A Q16665 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
CYP2C19 P33261 3/20 0.67
ALOX15 P16050 3/20 0.67
ALOX12 P18054 3/20 0.67
CYP1A2 P05177 3/20 0.67
HSP90AA1 P07900 3/20 0.67
MAPK1 P28482 2/20 0.67
RECQL P46063 2/20 0.67
THRB P10828 2/20 0.67
MEN1 O00255 2/20 0.67
LMNA P02545 2/20 0.67
HTR1A P08908 2/20 0.67
MAPT P10636 2/20 0.67
SLC6A2 P23975 2/20 0.67
HTT P42858 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8822888 0.81 HSD17B10 (0.76) HSD17B10TSHRHPGDCYP3A4HIF1A
SCHEMBL7716902 0.80 HSD17B10 (0.67) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL15579 0.80 HSD17B10 (1.00) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL29352805 0.80 HSD17B10 (1.00) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL2810158 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL19689282 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL16339207 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL11693520 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL2806744 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A
Hexachlorophene SCHEMBL3468532 0.78 HSD17B10 (0.95) HSD17B10TSHRHPGDCYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0333445-B1 Aromatic allene compounds and preparation thereof NIPPON PAINT CO LTD (JP) 1995-01-18 EP disclosed
US-5340931-A Chemical intermediates for allyl or vinyl ether polymers NIPPON PAINT CO., LTD. (JP) 1994-08-23 US disclosed
EP-0457334-B1 Carbonates of acetylenic alcohols NIPPON PAINT CO LTD (JP) 1994-08-10 EP disclosed
US-5258542-A Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1993-11-02 US disclosed
US-5194653-A Useful in making heat resistant liquid crystalline polymers NIPPON PAINT COMPANY, LIMITED (JP) 1993-03-16 US disclosed
EP-0457334-A1 Carbonates of acetylenic alcohols NIPPON PAINT CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0333445-A2 Aromatic allene compounds and preparation thereof NIPPON PAINT CO., LTD. (JP) 1989-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885TSHR 3263/4885HPGD 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.