Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724921 | 1.00 | NPC1 (0.62) | NPC1RAB9AHTR2BKDM4EMAPT | |
| SCHEMBL6756134 | 0.98 | NPC1 (0.59) | NPC1RAB9AHTR2BKDM4EMAPT | |
| SCHEMBL2674802 | 0.95 | HTR2B (0.55) | NPC1RAB9AHTR2BKDM4EMAPT | |
| SCHEMBL2276872 | 0.91 | ALDH1A1 (0.59) | NPC1RAB9AHTR2BKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL31596380 | 0.89 | MAPT (0.57) | NPC1RAB9AHTR2BKDM4EMAPT | |
| SCHEMBL665267 | 0.85 | PARP1 (0.59) | HTR2BKDM4EPOLB | |
| SCHEMBL531889 | 0.84 | PARP1 (0.52) | HTR2BMAPTNPY5RPOLB | |
| SCHEMBL2106423 | 0.84 | HTR2B (0.52) | HTR2BKDM4EMAPTGFERNPY5R | |
| SCHEMBL2491336 | 0.84 | HTR2B (0.52) | HTR2BMAPTNPY5RPOLB | |
| SCHEMBL20677809 | 0.83 | ALDH1A1 (0.52) | NPC1RAB9AHTR2BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |