Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670803 | 1.00 | PTPN11 (0.57) | PTPN11TSHRLMNAALDH1A1TP53 | |
| SCHEMBL17980842 | 0.93 | TSHR (0.53) | PTPN11TSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL8085142 | 0.91 | LMNA (0.60) | PTPN11TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL8081832 | 0.91 | LMNA (0.60) | PTPN11TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL8086789 | 0.91 | LMNA (0.60) | PTPN11TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL9417688 | 0.91 | LMNA (0.60) | PTPN11TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL342807 | 0.91 | PTPN11 (0.52) | PTPN11TSHRLMNAALDH1A1TP53 | |
| SCHEMBL8081846 | 0.91 | LMNA (0.60) | PTPN11TSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL11330301 | 0.91 | PTPN11 (0.52) | PTPN11TSHRLMNAALDH1A1TP53 | |
| SCHEMBL27676707 | 0.91 | PTPN11 (0.56) | PTPN11TSHRLMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713547-B2 | REACTING SWELLABLE LAYERED CLAY WITH PHOSPHONIUM OR QUATERNARY AMMONIUM COMPOUND, MELT MIXING, THEN MELT EXTRUDING THE EXPANDED CLAY AND POLYAMIDE | UNIVERSITY OF SOUTH CAROLINA RESEARCH FOUNDATION | 2004-03-30 | — | — | US | disclosed |
| EP-1040081-B1 | POLYMER NANOCOMPOSITES FOR HIGH GAS BARRIER APPLICATIONS | UNIV SOUTH CAROLINA RES FOUND (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6486252-B1 | Nanocomposites for high barrier applications | EASTMAN CHEMICAL COMPANY | 2002-11-26 | — | — | US | disclosed |
| US-20020169246-A1 | Process for preparing high barrier nanocomposites | EASTMAN CHEMICAL COMPANY | 2002-11-14 | — | — | US | disclosed |
| WO-2000078855-A9 | NANOCOMPOSITES FOR HIGH BARRIER APPLICATIONS | EASTMAN CHEM CO (US) | 2002-06-13 | — | — | WO | disclosed |
| WO-2000078855-A1 | NANOCOMPOSITES FOR HIGH BARRIER APPLICATIONS | EASTMAN CHEMICAL COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-1040081-A1 | POLYESTER NANOCOMPOSITES FOR HIGH BARRIER APPLICATIONS | EASTMAN CHEMICAL COMPANY (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6034163-A | ION EXCHANGED CLAY AND EXPANSION AGENT | EASTMAN CHEMICAL COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| WO-1999032403-A1 | POLYESTER NANOCOMPOSITES FOR HIGH BARRIER APPLICATIONS | EASTMAN CHEMICAL COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |