Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | PI4KA | P42356 | 3/20 | 0.60 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | AHCY | P23526 | 8/20 | 0.52 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.49 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753737 | 0.86 | ADORA2A (0.55) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL9836332 | 0.83 | AHCY (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19575549 | 0.83 | AHCY (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10172077 | 0.81 | ADORA2A (0.59) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7442359 | 0.78 | ADORA2A (0.51) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23680075 | 0.78 | AHCY (0.49) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10172072 | 0.77 | ADORA2A (0.58) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10172012 | 0.77 | ADORA2A (0.58) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL19575550 | 0.77 | PI4KA (0.50) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11222112 | 0.76 | ADORA2A (0.80) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438052-A1 | INHIBITORS OF HUMAN PHOSPHATIDYL−INOSITOL 3−KINASE DELTA | ICOS CORPORATION (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035075-A1 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2003-05-01 | — | — | WO | disclosed |