Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758070 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| SCHEMBL4969803 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1FBP1TP53 | |
| SCHEMBL4969807 | 0.89 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1FBP1TP53 | |
| Cinnamaldehyde SCHEMBL31442616 | 0.88 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| Paraben SCHEMBL28178094 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| Paraben SCHEMBL10713759 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| 4-Chloro-Benzoic Acid SCHEMBL31442509 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| Cinnamaldehyde SCHEMBL31442682 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EMAPK1TRPA1 | |
| SCHEMBL2615887 | 0.84 | ALDH1A1 (0.68) | ALDH1A1FBP1TP53TSHRKMT2A | |
| SCHEMBL69167 | 0.84 | ALDH1A1 (0.68) | ALDH1A1FBP1TP53TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |
| US-20040009956-A1 | Inhibition of protein tyrosine phosphatases and SH2 domains by a neutral phosphotyrosine mimetic | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-15 | — | — | US | disclosed |
| WO-2003093498-A1 | INHIBITION OF PROTEIN TYROSINE PHOSPHATASES AND SH2 DOMAINS BY A NEUTRAL PHOSPHOTYROSINE MIMETIC | THE OHIO STATE UNIVERSITY (US) | 2003-11-13 | — | — | WO | disclosed |
| EP-0073456-B1 | TETRAAZAANNULENE COBALT COMPLEX COMPOUNDS AND METHOD FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009956-A1 | Inhibition of protein tyrosine phosphatases and SH2 domains by a neutral phosphotyrosine mimetic | PTPRS, PTPRO, PTPN2 | ALDH1A1 2898/4885MAPT 3864/4885KDM4E 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.