SCHEMBL6758103

SCHEMBL6758103

COC(=COCC(C)C)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
MAP3K7 O43318 1/20 0.32
TAB1 Q15750 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11110067 0.78 ALOX15 (0.36)
SCHEMBL1900609 0.76 TSHR (0.36) TSHR
SCHEMBL569637 0.76 TSHR (0.36) TSHR
SCHEMBL27689525 0.74 TSHR (0.32) TSHR
SCHEMBL10663560 0.73 TSHR (0.34) TSHR
SCHEMBL1682712 0.72 GRIK1 (0.38)
SCHEMBL27938072 0.72
SCHEMBL27595893 0.71 TSHR (0.39) TSHRMAP3K7TAB1SMN1; SMN2
SCHEMBL7196350 0.70 TSHR (0.40) TSHRSMN1; SMN2
SCHEMBL13513774 0.67 TSHR (0.39) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883040-A For packing and applying the device and composition of the lotion comprising film forming agent and nonvolatile oil 莱雅公司 2018-11-23 CN disclosed
CN-108778235-A Device for applying the composition comprising film forming agent and nonvolatile oil for being in emulsion form 莱雅公司 2018-11-09 CN disclosed
CN-108601716-A Gel/gel-type composition based on pigments coated with hydrophobic substances and liquid fatty acid and/or diol compounds 莱雅公司 2018-09-28 CN disclosed
CN-108135807-A Anhydrous liquid composition comprising an oil, a film-forming polymer, a monol and a particulate material 莱雅公司 2018-06-08 CN disclosed
CN-104661645-B Copolymer with carbon siloxanes dendritic structure and include its composition and cosmetics 道康宁东丽株式会社 2018-05-15 CN disclosed
CN-107072928-A Emulsion comprising a silicone-based dendritic film-forming polymer and a silicone gum, treatment method using same and suitable device 莱雅公司 2017-08-18 CN disclosed
CN-106714773-A Emulsion comprising a silicone-based dendritic film-forming polymer and a pasty compound, treatment process using the same and suitable device 莱雅公司 2017-05-24 CN disclosed
CN-106170280-A Including with the cosmetic composition of the polymer of carbon siloxanes dendritic macromole unit and expanded polymer particles 欧莱雅 2016-11-30 CN disclosed
CN-103037836-B For the beauty method of making up to skin and/or lip and/or nursing OU LAIYA (FR) 2016-02-03 CN disclosed
CN-104661645-A Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DOW CORNING TORAY CO LTD 2015-05-27 CN disclosed
CN-102665668-B Copolymer having carbosiloxane dendrimer structure, and composition and cosmetic containing the same DOW CORNING TORAY CO.,LTD. (JP) 2014-10-22 CN disclosed
CN-103458861-A Composition comprising perlite and a polymer bearing a carbosiloxane dendrimer-based unit OREAL 2013-12-18 CN disclosed
CN-103037836-A Cosmetic process for making-up and/or caring for the skin and/or the lips OREAL 2013-04-10 CN disclosed
CN-102665668-A Copolymer having carbosiloxane dendrimer structure, and composition and cosmetic containing the same DOW CORNING TORAY CO LTD 2012-09-12 CN disclosed
CN-102026682-A Cosmetic makeup and/or care method using silicone resin and film-forming polymer OREAL 2011-04-20 CN disclosed
WO-2004076560-A1 THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-09-10 WO disclosed
WO-2004076547-A1 INORGANIC-POWDER TREATMENT AGENT, INORGANIC POWDER TREATED WITH THE SAME, AND THERMOPLASTIC RESIN COMPOSITION DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-09-10 WO disclosed