Styrene

Styrene

SCHEMBL675873

C=C(C)C(=O)O.C=CC=C.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
AKR1C3 P42330 1/20 0.48
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTT P42858 1/20 0.41
PTGS2 P35354 1/20 0.41
HPGD P15428 1/20 0.40
CYP3A4 P08684 1/20 0.40
KDM4E B2RXH2 1/20 0.39
AKR1C1 Q04828 1/20 0.38
RECQL P46063 2/20 0.38
CYP2C19 P33261 1/20 0.38
AKT1 P31749 1/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28240956 1.00 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL7214915 1.00 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL196270 1.00 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL6040755 0.96 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL11590663 0.96 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL76985 0.96 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL7753037 0.96 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL1680068 0.96 ALDH1A1 (0.61) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL10482120 0.94 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1
Styrene SCHEMBL22396598 0.94 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3GLATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9062200-B2 Polyester blends exhibiting low temperature toughness GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2015-06-23 US disclosed
US-20140357797-A1 POLYESTER BLENDS EXHIBITING LOW TEMPERATURE TOUGHNESS GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2014-12-04 US disclosed
US-8859681-B2 Polyester blends exhibiting low temperature toughness GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2014-10-14 US disclosed
EP-2152805-B1 POLYESTER BLENDS EXHIBITING LOW TEMPERATURE TOUGHNESS GRUPO PETROTEMEX SA DE CV (MX) 2014-05-21 EP disclosed
US-20110318519-A1 POLYESTER BLENDS EXHIBITING LOW TEMPERATURE TOUGHNESS GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2011-12-29 US disclosed
US-8058360-B2 Polyester blends exhibiting low temperature toughness GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2011-11-15 US disclosed
EP-2152805-A2 POLYESTER BLENDS EXHIBITING LOW TEMPERATURE TOUGHNESS Eastman Chemical Company (US) 2010-02-17 EP disclosed
WO-2008153688-A2 POLYESTER BLENDS EXHIBITING LOW TEMPERATURE TOUGHNESS EASTMAN CHEMICAL COMPANY (US) 2008-12-18 WO disclosed
US-20080299344-A1 Polyester blends exhibiting low temperature toughness ALPEK POLYESTER, S.A. DE C.V. (MX) 2008-12-04 US disclosed
WO-2000023520-A1 POLYESTER ARTICLES HAVING IMPROVED IMPACT STRENGTH EASTMAN CHEMICAL COMPANY (US) 2000-04-27 WO disclosed
WO-2000015716-A2 HIGH IMPACT POLYESTER BLENDS EASTMAN CHEMICAL COMPANY (US) 2000-03-23 WO disclosed