⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928895 | 0.67 | — | — | |
| SCHEMBL1708922 | 0.67 | — | — | |
| SCHEMBL220469 | 0.67 | — | — | |
| SCHEMBL16612581 | 0.62 | — | — | |
| SCHEMBL12293895 | 0.62 | — | — | |
| SCHEMBL11261047 | 0.60 | — | — | |
| SCHEMBL48363 | 0.59 | — | — | |
| SCHEMBL2491333 | 0.57 | — | — | |
| SCHEMBL14536423 | 0.56 | — | — | |
| SCHEMBL2172251 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214873-A1 | Use of amino-isoxazolidone compounds for improvement of implicit memory | G. D. SEARLE & CO. | 2004-10-28 | — | — | US | disclosed |
| US-20040214873-A1 | Use of amino-isoxazolidone compounds for improvement of implicit memory | G. D. SEARLE & CO. | 2004-10-28 | — | — | US | disclosed |
| US-20040214873-A1 | Use of amino-isoxazolidone compounds for improvement of implicit memory | G. D. SEARLE & CO. | 2004-10-28 | — | — | US | disclosed |
| US-6656962-B2 | Administering a therapeutically-effective amount of a glycine B partial agonist to improve implicit memory | PHARMACIA CORPORATION | 2003-12-02 | — | — | US | disclosed |
| US-6656962-B2 | Administering a therapeutically-effective amount of a glycine B partial agonist to improve implicit memory | PHARMACIA CORPORATION | 2003-12-02 | — | — | US | disclosed |
| US-6656962-B2 | Administering a therapeutically-effective amount of a glycine B partial agonist to improve implicit memory | PHARMACIA CORPORATION | 2003-12-02 | — | — | US | disclosed |
| US-20030073730-A1 | Use of amino-isoxazolidone compounds for treatment of memory impairment following traumatic brain injury | G.D. SEARLE & CO. (US) | 2003-04-17 | — | — | US | disclosed |
| US-20030073730-A1 | Use of amino-isoxazolidone compounds for treatment of memory impairment following traumatic brain injury | G.D. SEARLE & CO. (US) | 2003-04-17 | — | — | US | disclosed |
| US-20030073730-A1 | Use of amino-isoxazolidone compounds for treatment of memory impairment following traumatic brain injury | G.D. SEARLE & CO. (US) | 2003-04-17 | — | — | US | disclosed |
| US-20020183373-A1 | Use of amino-isoxazolidone compounds for improvement of lexical priming | G.D. SEARLE & CO. | 2002-12-05 | — | — | US | disclosed |
| WO-1996015788-A1 | USE OF AMINO-ISOXAZOLIDONE COMPOUNDS FOR IMPROVEMENT OF IMPLICIT MEMORY | G.D. SEARLE & CO. (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996015788-A1 | USE OF AMINO-ISOXAZOLIDONE COMPOUNDS FOR IMPROVEMENT OF IMPLICIT MEMORY | G.D. SEARLE & CO. (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996015787-A1 | USE OF AMINO-ISOXAZOLIDONE COMPOUNDS FOR TREATMENT OF MEMORY IMPAIRMENT FOLLOWING TRAUMATIC BRAIN INJURY | G.D. SEARLE & CO. (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996015787-A1 | USE OF AMINO-ISOXAZOLIDONE COMPOUNDS FOR TREATMENT OF MEMORY IMPAIRMENT FOLLOWING TRAUMATIC BRAIN INJURY | G.D. SEARLE & CO. (US) | 1996-05-30 | — | — | WO | disclosed |
| US-5187171-A | USE OF A GLYCINE B PARTIAL AGONIST AS AN ANTIPSYCHOTIC | G. D. SEARLE & CO. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5187171-A | USE OF A GLYCINE B PARTIAL AGONIST AS AN ANTIPSYCHOTIC | G. D. SEARLE & CO. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0378134-A3 | USE OF A GLYCINE B PARTIAL AGONIST AS AN ANTIPSYCHOTIC | G.D. Searle & Co. (US) | 1991-07-17 | — | — | EP | disclosed |
| US-4999267-A | ELECTROGRAPHY | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0378134-A2 | Use of a glycine B partial agonist as an antipsychotic | G.D. Searle & Co. (US) | 1990-07-18 | — | — | EP | disclosed |
| EP-0378134-A2 | Use of a glycine B partial agonist as an antipsychotic | G.D. Searle & Co. (US) | 1990-07-18 | — | — | EP | disclosed |