SCHEMBL675973

SCHEMBL675973

C=CC[Sn](CCCCCCCC)(CCCCCCCC)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.48
ALDH1A1 P00352 3/20 0.40
THRB P10828 1/20 0.38
FAAH O00519 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
DNM1 Q05193 4/20 0.31
LMNA P02545 2/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15018741 0.95 TSHR (0.48) TSHRALDH1A1THRBFAAHZDHHC20
SCHEMBL29131476 0.95 TSHR (0.42) TSHRALDH1A1THRBFAAH
SCHEMBL3639103 0.93 TSHR (0.44) TSHRALDH1A1THRBFAAHZDHHC20
SCHEMBL124655 0.90 TSHR (0.43) TSHRALDH1A1LMNA
SCHEMBL385253 0.85 TSHR (0.43) TSHRALDH1A1LMNA
SCHEMBL1029360 0.85 TSHR (0.43) TSHRALDH1A1LMNA
SCHEMBL7634991 0.79 TSHR (0.38) TSHRALDH1A1
Pentane SCHEMBL10676495 0.79 TSHR (0.48) TSHRALDH1A1THRBFAAHLMNA
SCHEMBL29101465 0.77 TSHR (0.62) TSHRALDH1A1THRBFAAHDNM1
SCHEMBL11607766 0.76 TSHR (0.54) TSHRALDH1A1THRBFAAHDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2791230-B1 UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS DU PONT (US) 2015-09-16 EP claimed
US-9074074-B2 Polyhydroxy curable fluoroelastomer compositions THE CHEMOURS COMPANY FC, LLC (US) 2015-07-07 US claimed
EP-2791230-A1 UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS E. I. Du Pont de Nemours and Company (US) 2014-10-22 EP claimed
WO-2013090535-A1 UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 WO claimed
US-20130158200-A1 POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 US claimed
WO-2013090582-A1 POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 WO claimed
US-20130158155-A1 COAGENT FOR FREE RADICAL CURING CHLOROROELASTOMERS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 US claimed
US-20130158154-A1 COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS E.I.DU PONT DE NEMOURS AND COMPANY (US) 2013-06-20 US claimed
EP-2223946-B1 Modified natural rubber or modified natural rubber latex and rubber composition BRIDGESTONE CORP (JP) 2012-08-22 EP claimed
CN-114630870-B Resin composition 三键有限公司 2023-09-15 CN disclosed
US-20220396650-A1 RESIN COMPOSITION THREEBOND CO., LTD. (JP) 2022-12-15 US disclosed
EP-4053205-A1 RESIN COMPOSITION ThreeBond Co., Ltd. (JP) 2022-09-07 EP disclosed
CN-114630870-A Resin composition 三键有限公司 2022-06-14 CN disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-6274688-B1 CROSSLINKING KANEKA CORPORATION (JP) 2001-08-14 US disclosed
EP-1000980-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2000-05-17 EP disclosed
EP-1000979-A1 CURABLE ADHESIVE COMPOSITION KANEKA CORPORATION (JP) 2000-05-17 EP disclosed
EP-0992519-A1 BLOCK COPOLYMER KANEKA CORPORATION (JP) 2000-04-12 EP disclosed
US-5986014-A SILYL GROUPS ON (METH)ACRYLIC POLYMERS FORMED BY REACTION OF HALOGEN GROUPS KANEKA CORPORATION (JP) 1999-11-16 US disclosed
EP-0789036-A2 Processes for preparing (meth)-acrylic polymers having functional groups at the chain ends Kaneka Corporation (JP) 1997-08-13 EP disclosed