SCHEMBL385253

SCHEMBL385253

C=CC[Sn](CC=C)(CCCC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124655 0.95 TSHR (0.43) TSHRALDH1A1LMNA
SCHEMBL1029360 0.95 TSHR (0.43) TSHRALDH1A1LMNA
SCHEMBL29131476 0.90 TSHR (0.42) TSHRALDH1A1
SCHEMBL15018741 0.90 TSHR (0.48) TSHRALDH1A1LMNA
SCHEMBL3639103 0.87 TSHR (0.44) TSHRALDH1A1
SCHEMBL675973 0.85 TSHR (0.48) TSHRALDH1A1LMNA
Pentane SCHEMBL10676495 0.83 TSHR (0.48) TSHRALDH1A1LMNA
SCHEMBL643466 0.80 TSHR (0.32) TSHRALDH1A1
SCHEMBL7634991 0.78 TSHR (0.38) TSHRALDH1A1
SCHEMBL6551771 0.77 TSHR (0.62) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
EP-0342493-A2 Tin-containing copolymers, and their use BASF Aktiengesellschaft (DE) 1989-11-23 EP claimed
US-10995165-B2 Catalyst composition for preparing conjugated diene-based polymer and conjugated diene-based polymer prepared using the same LG CHEM, LTD. 2021-05-04 US disclosed
EP-3315520-B1 CATALYST COMPOSITION FOR PREPARING CONJUGATED DIENE POLYMER AND CONJUGATED DIENE POLYMER PREPARED BY MEANS OF SAME LG CHEMICAL LTD (KR) 2019-12-18 EP disclosed
EP-3315520-A1 CATALYST COMPOSITION FOR PREPARING CONJUGATED DIENE POLYMER AND CONJUGATED DIENE POLYMER PREPARED BY MEANS OF SAME LG Chem, Ltd. (KR) 2018-05-02 EP disclosed
US-20180030174-A1 CATALYST COMPOSITION FOR PREPARING CONJUGATED DIENE-BASED POLYMER AND CONJUGATED DIENE-BASED POLYMER PREPARED USING THE SAME LG CHEM, LTD. (KR) 2018-02-01 US disclosed
EP-2791230-B1 UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS DU PONT (US) 2015-09-16 EP disclosed
US-9074074-B2 Polyhydroxy curable fluoroelastomer compositions THE CHEMOURS COMPANY FC, LLC (US) 2015-07-07 US disclosed
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2015-03-19 US disclosed
EP-2397475-B1 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same IMEC (BE) 2014-11-12 EP disclosed
EP-0781821-A2 Polyester powder coating composition SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-02 EP disclosed
US-5587420-A WEAR RESISTANT, FRICTION RESISTANT TIRE BRIDGESTONE CORPORATION (JP) 1996-12-24 US disclosed
US-5534378-A LAYER OF DIELECTRIC AND ONE CONTROLLING ELECTROSTATIC CHARGE OF TONER; QUALITY, DURABILITY BASF AKTIENGESELLSCHAFT (DE) 1996-07-09 US disclosed
US-5516458-A TIN CARBOXYLATE, ANTIMONY ALKOXIDE, POLYVINYL BUTYRAL, BUTANOL EASTMAN KODAK COMPANY (US) 1996-05-14 US disclosed
EP-0637072-A2 Spin-on conductor process for integrated circuits AT&T GLOBAL INFORMATION SOLUTIONS INTERNATIONAL INC. (US) 1995-02-01 EP disclosed
EP-0383002-B1 Coated concrete roof BASF AG (DE) 1994-06-22 EP disclosed
US-5047295-A Hydrazide Crosslinked Addition Interpolymer Containing Tin BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0383002-A1 Coated concrete roof BASF Aktiengesellschaft (DE) 1990-08-22 EP disclosed
EP-0342493-A2 Tin-containing copolymers, and their use BASF Aktiengesellschaft (DE) 1989-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 TSHR 4359/4885ALDH1A1 3595/4885LMNA 1616/4885
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS APEX1, SOD1, AP1M1 TSHR 4417/4885ALDH1A1 1713/4885LMNA 4135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.