SCHEMBL676002

SCHEMBL676002

COc1cc(Cl)ccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30078861 1.00
SCHEMBL30954867 0.85
SCHEMBL170306 0.78 MAPT (0.42)
SCHEMBL14349236 0.78 NUDT1 (0.50)
SCHEMBL7051326 0.77
SCHEMBL22730339 0.77 KDM4E (0.41)
SCHEMBL30626327 0.76 LOX (0.55)
SCHEMBL127715 0.76
SCHEMBL29424138 0.76
SCHEMBL16116782 0.76 LOX (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113264919-A Preparation method of 1- (2-methoxypyridin-4-yl) -1H-pyrazol-4-amine 无锡捷化医药科技有限公司 2021-08-17 CN claimed
US-20190353307-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS HARBISON-FISCHER, INC. 2019-11-21 US claimed
EP-3420055-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS Ecolab USA Inc. (US) 2019-01-02 EP claimed
WO-2017147426-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS ECOLAB USA INC. (US) 2017-08-31 WO claimed
US-20170248276-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS US SYNTHETIC CORPORATION 2017-08-31 US claimed
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2025-07-24 US disclosed
US-12275728-B2 O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2025-04-15 US disclosed
EP-3420055-B1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS CHAMPIONX LLC (US) 2025-04-09 EP disclosed
US-20250084064-A1 2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS MERCK SHARP & DOHME LLC (US) 2025-03-13 US disclosed
US-12195445-B2 2-amino-N-heteroaryl-nicotinamides as Nav1.8 inhibitors MERCK SHARP & DOHME LLC (US) 2025-01-14 US disclosed
US-12180205-B2 O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors BIOGEN MA INC. (US) 2024-12-31 US disclosed
US-20240308995-A1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS BIOGEN MA INC. 2024-09-19 US disclosed
EP-1304325-A1 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-04-23 EP disclosed
US-20030065208-A1 Using palladium, nickel phosphine complex as catalysts MITSUBISHI RAYON CO., LTD. (JP) 2003-04-03 US disclosed
EP-1196393-B1 METHOD FOR PRODUCING 4,6-DICHLOROPYRIMIDINE BAYER AG (DE) 2003-04-02 EP disclosed
EP-1270582-A1 TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE Mitsubishi Rayon Co., Ltd. (JP) 2003-01-02 EP disclosed
CN-1085218-C Olefin polymerization catalyst ASAHI CHEMICAL IND (JP) 2002-05-22 CN disclosed
EP-1196393-A2 METHOD FOR PRODUCING 4,6-DICHLOROPYRIMIDINE Bayer Aktiengesellschaft (DE) 2002-04-17 EP disclosed
WO-2001000591-A2 METHOD FOR PRODUCING 4,6-DICHLOROPYRIMIDINE BAYER AKTIENGESELLSCHAFT (DE) 2001-01-04 WO disclosed
US-4167567-A Antihypertensive 4-aminoquinolines THE UPJOHN COMPANY (US) 1979-09-11 US disclosed