⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Nitrosodimethylamine SCHEMBL28300409 | 0.73 | — | — | |
| SCHEMBL27657233 | 0.70 | — | — | |
| N-Nitrosodimethylamine SCHEMBL686 | 0.70 | — | — | |
| N-Nitrosodimethylamine SCHEMBL4637228 | 0.70 | ALDH1A1 (1.00) | — | |
| Hydrochloric Acid SCHEMBL9537 | 0.68 | — | — | |
| SCHEMBL13180581 | 0.67 | — | — | |
| N-Nitrosodimethylamine SCHEMBL28019810 | 0.67 | — | — | |
| N-Nitrosodimethylamine SCHEMBL19971881 | 0.67 | — | — | |
| Trimethylammonium SCHEMBL6550503 | 0.67 | — | — | |
| N-Nitrosodimethylamine SCHEMBL11862028 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054028-A1 | BACTERIAL SIDEROPHORE GRAMIBACTIN | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut (DE) | 2021-02-25 | — | — | US | disclosed |
| US-20160228460-A1 | NITROXYL PROGENITORS IN THE TREATMENT OF HEART FAILURE | NIH - DEITR | 2016-08-11 | — | — | US | disclosed |
| US-9114071-B2 | Oral pharmaceutical composition | SIGMOID PHARMA LIMITED (IE) | 2015-08-25 | — | — | US | disclosed |
| US-8980870-B2 | Solid telmisartan pharmaceutical formulations | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20150004259-A1 | NITROXYL PROGENITORS IN THE TREATMENT OF HEART FAILURE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-01-01 | — | — | US | disclosed |
| US-20130280855-A1 | METHOD FOR PRODUCING COMPOUND HAVING CHALCOPYRITE STRUCTURE | TOHOKU SEIKI INDUSTRIES, CO., LTD. (JP) | 2013-10-24 | — | — | US | disclosed |
| US-8482504-B2 | Liquid crystal display device and method of driving the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20130138155-A1 | Bone Regeneration Membrane and Method for Forming a Bone Regeneration Membrane | CHU NANTES (FR) | 2013-05-30 | — | — | US | disclosed |
| WO-2013058833-A1 | COMPOSITIONS COMPRISING ALKALINE PHOSPHATASE AND/OR NATRIURETIC PEPTIDE AND METHODS OF USE THEREOF | ENOBIA CANADA LIMITED PARTNERSHIP (CA) | 2013-04-25 | — | — | WO | disclosed |
| EP-2032160-B2 | VACCINE | GLAXOSMITHKLINE BIOLOG SA (BE) | 2013-04-03 | — | — | EP | disclosed |
| US-7799335-B2 | Differential delivery of nitric oxide | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20090246296-A1 | METHOD OF TREATING ISCHEMIA/REPERFUSION INJURY WITH NITROXYL DONORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-10-01 | — | — | US | disclosed |
| US-7425218-B2 | Nitric oxide-releasing medical devices | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-09-16 | — | — | US | disclosed |
| US-7311858-B2 | Barium, calcium, cadmium, magnesium, strontium, or zinc silicate doped with europium, and fluorine, iodine, chlorine, bromine, nitrogen, phosphorus, and/or sulfur; configured to absorb visible light from a blue light emitting diode (LED); white LEDs; YAG lasers | INTEMATIX CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7226586-B2 | Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use | MEDTRONIC VASCULAR, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| US-20070087025-A1 | Reiteratively layered medical devices and method of preparing same | FITZHUGH ANTHONY | 2007-04-19 | — | — | US | disclosed |
| US-20070059338-A1 | Compositions and techniques for localized therapy | KNAPP DAVID | 2007-03-15 | — | — | US | disclosed |
| US-20070048297-A1 | Human secreted proteins | HUMAN GENOME SCIENCES, INC. (US) | 2007-03-01 | — | — | US | disclosed |
| US-20070014828-A1 | Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same | GOVERNMENT OF THE USA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2007-01-18 | — | — | US | disclosed |
| US-4144260-A | Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |