Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770572 | 1.00 | HSD11B1 (0.46) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL12779468 | 0.97 | LTB4R2 (0.42) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL2769407 | 0.97 | LTB4R2 (0.42) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL3185777 | 0.97 | LTB4R2 (0.42) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL2773665 | 0.97 | LTB4R2 (0.42) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL20056954 | 0.97 | LTB4R2 (0.42) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL2771243 | 0.97 | HSD11B1 (0.48) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL2772632 | 0.94 | HSD11B1 (0.43) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL258125 | 0.94 | HSD11B1 (0.43) | HSD11B1CNR2LTB4R2RARBALDH1A1 | |
| SCHEMBL2292411 | 0.94 | HSD11B1 (0.43) | HSD11B1CNR2LTB4R2RARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067427-A1 | Flexible support substrate with an electroconductive layer, a charge blocking, charge generating and a charge transporting layer of aromatic bis tertiary amines; electrophotography | XEROX CORPORATION | 2004-04-08 | — | — | US | claimed |